Antisuppressor
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Antisuppressor is a mutation with the response against suppression effects of nonsense suppression or suppression chemicals.[1][2][3][2]
In 1976, Rieger, Michaelis, and Green have been stated: {{Quote|"antisuppressor – a mutation which countreacts suppressor effects (→ nonsense suppression). Antisuppressor mutations can occur in any of the folowing components affecting the → genetic translation system (Cox 1973):
- A ribosomal component affecting codon-anticodon recognition or tRNA binding.
- A termination factor altered in such a way that synthesis polypeptide release from the ribosome is enhanced thus decreasing the efficiency of suppression.
- An enzyme affecting → suppressor tRNA (either an → aminoacyl-tRNA synthetase, a base modifying enzyme affecting the anticodon, an enzyme modifaying a base or bases involved in ribosome binding, an enzyme affecting tRNA maturation, or a factor controling total tRNA)."[1]
See also
[change | change source]References
[change | change source]- ↑ 1.0 1.1 Rieger, R.; Michaelis, A.; Green, M. M. (1976). Glossary of Genetics and Cytogenetics: Classical and Molecular. Heidelberg - New York: Springer-Verlag. ISBN 3-540-07668-9.
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: CS1 maint: multiple names: authors list (link) - ↑ 2.0 2.1 King, R. C.; Stansfield, W. D. (1998). Dictionary of Genetics. New York, Oxford: Oxford University Press. ISBN 0-19-50944-1-7.
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: CS1 maint: multiple names: authors list (link) - ↑ Hadžiselimović, R.; Pojskić, N. (2005). Uvod u humanu imunogenetiku. Institut za genetičko inženjerstvo i biotehnologiju (INGEB), Sarajevo. ISBN 9958-9344-3-4.
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: CS1 maint: multiple names: authors list (link)