Jump to content

Drug tolerance

From Simple English Wikipedia, the free encyclopedia

Drug tolerance (or physiological tolerance) is a term used to describe that the organism gets used to a given substance. Drug tolerance also means that over time a drug becomes less effective and larger amounts of the substance are needed to get the same effect.[1]

Physiological tolerance can be achieved in one of the following ways:

  1. By changing the number of receptors for a substance
  2. By changing the way the signal is handled
  3. By changing the receptors themselves
  4. By changing the system that antagonizes the receptor

References

[change | change source]
  1. ↑ "How Do Drug Tolerance and Dependency Set In?". Sunrise House. Retrieved 2020-11-24.
Retrieved from "https://simple.wikipedia.org/w/index.php?title=Drug_tolerance&oldid=8996911"