User:Mr. Ibrahem/PUVA therapy
Template:Infobox interventions PUVA (psoralen and ultraviolet A) is an ultraviolet light therapy treatment for skin diseases: eczema, psoriasis, graft-versus-host disease, vitiligo, mycosis fungoides, large plaque parapsoriasis and cutaneous T-cell lymphoma using the sensitizing effects of the drug psoralen.[1]: 686 [2][3] The psoralen is applied or taken orally to sensitize the skin, then the skin is exposed to UVA.
Photodynamic therapy is the general use of nontoxic light-sensitive compounds that are exposed selectively to light, whereupon they become toxic to targeted malignant and other diseased cells. Still, PUVA therapy is often classified as a separate technique from photodynamic therapy.[4][5]
References
[change | change source]- ↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ↑ Domínguez MA, Membrillo VG, Ramos GA (2004). "Large plaque parapsoriasis and PUVA-therapy. A case report". Archived from the original on 2012-07-12. Retrieved 2012-03-23.
- ↑ MacMillan Cancer Support Group. "Cutaneous T-cell lymphoma (CTCL)". Archived from the original on 2014-10-23. Retrieved 2021-03-02.
- ↑ Finlan, L. E.; Kernohan, N. M.; Thomson, G.; Beattie, P. E.; Hupp, T. R.; Ibbotson, S. H. (2005). "Differential effects of 5-aminolaevulinic acid photodynamic therapy and psoralen + ultraviolet a therapy on p53 phosphorylation in normal human skin in vivo". British Journal of Dermatology. 153 (5): 1001–10. doi:10.1111/j.1365-2133.2005.06922.x. PMID 16225614.
- ↑ Champva Policy Manual, Chapter: 2, Section: 30.11, Title: PDT (Photodynamic Therapy) and PUVA (Photochemotherapy) Archived 2012-01-14 at the Wayback Machine at U.S. Department of Veterans Affairs. Date: 12/23/2011