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User:Mr. Ibrahem/Vonoprazan/amoxicillin/clarithromycin

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Mr. Ibrahem/Vonoprazan/amoxicillin/clarithromycin
Combination of
VonoprazanPotassium-competitive acid blocker
AmoxicillinBeta-lactam antibiotic
ClarithromycinMacrolide antibiotic
Clinical data
Trade namesVonosap, Voquezna triple pak
AHFS/Drugs.comMonograph
License data
Legal status
Legal status

Vonoprazan/amoxicillin/clarithromycin, sold under the brand name Vonosap among others, is a co-packaged medication used to treat Helicobacter pylori (H. pylori) infection.[1] It is taken by mouth.[1]

Common side effects include diarrhea, vaginal yeast infection, headache, abdominal pain, and high blood pressure.[1] Other side effects may include allergic reaction, Clostridioides difficile-associated diarrhea, QT prolongation.[1] Use is generally not recommended in pregnancy.[1] It contains vonoprazan, a potassium-competitive acid blocker; amoxicillin, a beta-lactam antibiotic; and clarithromycin, a macrolide antibiotic.[1]

The combination was approved for medical use in Japan in 2016,[2] and the United States in 2022.[1] In the United States a course of treatment costs about 860 USD as of 2022.[3] As of 2022 it is not avaliable in Europe or the United Kingdom.[4]

References

[change | change source]
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 "Voquezna Dual Pak- vonoprazan fumarate and amoxicillin kit Voquezna Triple Pak- vonoprazan fumarate, amoxicillin and clarithromycin kit". DailyMed. 21 June 2022. Archived from the original on 3 July 2022. Retrieved 3 July 2022.
  2. 2.0 2.1 "Vonosap pack 400, Vonosap pack 800 and Vonopion pack (triple-drug blister packs containing Takecab tablet) Now Available for Helicobacter pylori[*] Eradication in Japan". Takeda. 7 June 2016. Archived from the original on 10 May 2022. Retrieved 9 May 2022.
  3. "Voquezna Triple Pak Prices, Coupons, Copay & Patient Assistance". Drugs.com. Retrieved 12 December 2022.
  4. "Vonoprazan". SPS - Specialist Pharmacy Service. 10 December 2019. Archived from the original on 25 September 2021. Retrieved 12 December 2022.