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Nifedipine

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Nifedipine
Clinical data
Trade namesAdalat, Procardia, others
AHFS/Drugs.comMonograph
MedlinePlusa684028
License data
Pregnancy
category
Routes of
administration
By mouth, topical
Drug classCalcium channel blocker (dihydropyridine)[2]
ATC code
Pharmacokinetic data
Bioavailability45-56%
Protein binding92-98%
MetabolismGastrointestinal, Liver
Elimination half-life2 hours
ExcretionKidneys: >50%, bile duct: 5-15%
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard100.040.529 Edit this at Wikidata
  (verify)

Nifedipine (brand names: Adalat, Adipine, Coracten, Fortipine, Nifedipress) is a calcium channel blocker medicine used to treat high blood pressure (hypertension).[3]

In people with high blood pressure, taking nifedipine helps to prevent future heart disease, heart attacks and strokes.[3] Nifedipine is also used to prevent chest pain caused by angina. Occasionally, it is used to treat Raynaud's phenomenon and chilblains.[3]

Related pages[change | change source]

References[change | change source]

  1. "Nifedipine Pregnancy and Breastfeeding Warnings". Archived from the original on 21 December 2015. Retrieved 25 December 2015.
  2. "Nifedipine". The American Society of Health-System Pharmacists. Archived from the original on 8 August 2018. Retrieved 17 September 2019.
  3. 3.0 3.1 3.2 "About nifedipine". nhs.uk. 2022-02-25. Retrieved 2024-05-30.